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| Drew Barrymore | Charlene McGee | |
| David Keith | Andrew McGee | |
| Freddie Jones | Doctor Joseph Wanless | |
| Heather Locklear | Victoria Tomlinson McGee | |
| Martin Sheen | Captain Hollister | |
| George C. Scott | John Rainbird | |
| Art Carney | Irv Manders | |
| Louise Fletcher | Norma Manders | |
| Moses Gunn | Doctor Pynchot | |
| Antonio Fargas | Taxi Driver | |
| Drew Snyder | Orville Jamieson | |
| Curtis Credel | Bates | |
| Keith Colbert | Mayo | |
| Dick Warlock | Knowles | |
| Jeff Ramsey | Steinowitz |
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| Producer | Martha De Laurentiis
Frank Capra Jr. |
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| Writer | Stephen King
Stanley Mann |
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| Cinematography | Giuseppe Ruzzolini
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| Musician | Christopher Franke
Edgar Froese |
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A couple who participated in a potent medical experiment gain telekinetic ability and then have a child who is pyrokinetic. |
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